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For people with known heart disease who, along with diet and a statin, need more help lowering their bad cholesterol (LDL-C).
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With 2 doses a year,* LEQVIO® plus a statin is proven to cut bad cholesterol (LDL-C) in half and keep it low

Individual results may vary.

*2 doses a year after 2 initial doses.

People given LEQVIO lowered their bad cholesterol (LDL-C) more and kept it low during each 6-month dosing interval vs placebo (a substance that doesn't contain any medication).

Lower. Longer. LEQVIO.*

LEQVIO is the only cholesterol-lowering medication that’s given by your doctor or other health care provider every 6 months after 2 initial doses. With LEQVIO, lowering bad cholesterol can fit into your twice-yearly doctor visits.

LEQVIO is an injection given at your doctor’s office that is 2 doses a year after 2 initial doses. In clinical studies, people taking LEQVIO with a maximally tolerated statin lowered their bad cholesterol by over 50% and kept it low during each 6-month dosing interval vs placebo.

Individual results may vary.

Clinical study information

These results are based on a study in which 1561 patients with atherosclerotic cardiovascular disease (ASCVD) were on a maximally tolerated statin with or without another cholesterol-lowering treatment—in addition to LEQVIO (781 patients) or a placebo (780 patients). Cholesterol levels were measured at the start of the study and compared with cholesterol levels 17 months later. Sixty percent of the patients were 65 years or older. LEQVIO was also studied in an identical clinical trial of 1414 patients with similar results.

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Want to learn more about LEQVIO?

Choosing the right medication for you to further lower your bad cholesterol is an important decision to make with your doctor. Start the discussion today and find out how LEQVIO can help reduce bad cholesterol with 2 doses a year after 2 initial doses.

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Is LEQVIO affordable for me?

If you have commercial insurance, you may pay as little as $0 with the LEQVIO Co-pay Program.

Or if you have Medicare and supplemental insurance, you may pay as little as $0.§

Terms & Conditions  apply.  

§Data on file. LEQVIO Coverage and Affordability. Novartis Pharmaceuticals Corp; 2022.

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Tap to see Important Safety Information and Approved Use

Important Safety Information

The most common side effects of LEQVIO were: injection site reaction (including pain, redness, and rash), joint pain, urinary tract infection, diarrhea, chest cold, pain in legs or arms and shortness of breath.

These are not all the possible side effects of LEQVIO. Ask your health care provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit , or call 1-800-FDA-1088


What is LEQVIO? 
LEQVIO (inclisiran) is an injectable prescription medicine used along with diet and other lipid-lowering medicines in adults who need additional lowering of "bad" cholesterol (LDL-C) and have known cardiovascular disease and/or heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL-C. It is not known if LEQVIO can decrease problems related to high cholesterol, such as heart attacks or stroke